Only at 10 to 12 hours and 11 to 12 hours post-dose did Concerta 36 mg and 54 mg demonstrate symptom improvement over Focalin XR 20 mg and 30 mg respectively. Similar efficacy was observed between Focalin XR and Concerta at eight hours post-dose. The study included children between the ages of 6 and 12 and examined their response to Focalin XR compared to Concerta as well as placebo in a classroom setting.
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"The results of this study demonstrate the benefits of Focalin XR during the early part of the day, which may be better for children who need their medication to begin working before they leave for school and continue working throughout the day."Īttention Deficit/Hyperactivity Disorder affects approximately three to seven percent of children in the United States, and its symptoms - inattention, hyperactivity and impulsivity - can significantly impact a child's ability to focus and learn in an educational setting. "There are many things to consider when determining which treatment is best for a patient, including lifestyle implications," said Alice Mao, M.D., Associate Professor of Psychiatry at the Baylor College of Medicine. Novartis is seeking revised labeling to reflect the 30-minute onset of action.
![dexmethylphenidate er dexmethylphenidate er](http://images.medscape.com/pi/features/drugdirectory/octupdate/NOV06090.jpg)
Neither dose of Concerta was effective versus placebo at 30 minutes. Symptom control was demonstrated as early as 30 minutes post-dose with Focalin XR 20 mg and 30 mg versus placebo. EAST HANOVER, N.J., July 8 /PRNewswire/ - A head-to-head study, published in the June Journal of Child and Adolescent Psychopharmacology, confirms that Focalin(R) XR (dexmethylphenidate HCl) extended-release capsules offer greater improvements in managing symptoms of Attention Deficit/Hyperactivity Disorder compared with Concerta(R) (d,l- methylphenidate HCl) extended-release tablets at two hours post-dose, the primary study endpoint.įocalin XR 20 mg and 30 mg2 also demonstrated better symptom control versus Concerta 36 mg and 54 mg respectively, from 30 minutes to 6 hours.